Ethylenediaminetetraacetic acid
Ethylenediaminetetraacetic acid
CAS: 60-00-4
Molecular Formula: C10H16N2O8
Ethylenediaminetetraacetic acid - Names and Identifiers
| Name | Ethylenediaminetetraacetic acid |
| Synonyms | EDTA EDTA ACID Edetic acid EDTA-SOLUTION Ethylenediaminetetraacetic acid Ethylene diamine tetraacetic acid EDTA, 500 mM Solution, pH 8.0,ULTROL Grade 3,4-diamino-3,4-bis(carboxymethyl)hexanedioic acid EDTA, free acid Ethylenediamine tetraacetic acid, free acid 2,2'-{ethane-1,2-diylbis[(carboxymethyl)imino]}diacetate (non-preferred name) |
| CAS | 60-00-4 |
| EINECS | 200-449-4 |
| InChI | InChI=1/C10H16N2O8/c11-9(1-5(13)14,2-6(15)16)10(12,3-7(17)18)4-8(19)20/h1-4,11-12H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20) |
Ethylenediaminetetraacetic acid - Physico-chemical Properties
| Molecular Formula | C10H16N2O8 |
| Molar Mass | 292 |
| Density | 1.628g/cm3 |
| Melting Point | 237-245℃ (dec.) |
| Boling Point | 540.597°C at 760 mmHg |
| Flash Point | 280.743°C |
| Water Solubility | 0.5 g/L (25℃) |
| Solubility | The solubility in water at 25 ℃ is 0.5g/L. Insoluble in cold water, alcohols and general organic solvents. Soluble in sodium hydroxide, sodium carbonate and ammonia solution. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | White crystal |
| Storage Condition | Room Temprature |
| Refractive Index | 1.603 |
| MDL | MFCD00003541 |
| Physical and Chemical Properties | The character crystallized from water is white powder. solubility the solubility in water at 25 °c was 0.5g/L. Insoluble in cold water, alcohol and general organic solvents. Soluble in sodium hydroxide, sodium carbonate and ammonia solution. |
| Use | Used as dyeing aids, fiber treatment agents, cosmetic additives, blood anticoagulants, water treatment agents, rubber polymerization initiators, PVC heat stabilizers |
Ethylenediaminetetraacetic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
Ethylenediaminetetraacetic acid - Upstream Downstream Industry
Ethylenediaminetetraacetic acid - Reference
| Reference Show more | 1. Liu Lianjun, Li Ping, Li Hengrui, etc. Breeding of avermectin resistant strains of cassava cinnabar Spider mite and changes of its detoxification enzyme activity [J]. Jiangsu Agricultural Sciences, 2018, 046(023):94-97. 2. Luo Zheng, Guo Yuan-yuan, Chen Fei-ping, et al. Inhibition of key enzyme phenylalanine in lignification of Brassica campestris L. By high oxygen modified atmosphere packaging [J]. Food Research and Development, 2019, 40(08):36-40. 3. Zhang ningying, Chen Haiyan, Chen Hangjun. Effects of Ozone treatment on storage quality and antioxidant enzyme activities of blueberry [J]. Chinese Journal of Food Science, 2017, 17(008):170-176. 4. Li Tong, Zhao Na, Shi Yu, et al. Formulation optimization and percutaneous permeability of vitamin C Nanoemulsion [J]. Journal of Shenyang Pharmaceutical University, 2018(7). 5. Mihanbao, Lijun. Study on the difference of antioxidant activity of different cocoon color silk enzymatic hydrolysis products [J]. Agricultural science research 2017(3). 6. He, Baoshan, et al. "Aptamer-based thin film gold electrode modified with gold nanoparticles and carboxylated multi-walled carbon nanotubes for detecting oxytetracycline in chicken samples." Food chemistry 300 (2019): 125179.https://doi.org/10.1016/j.foodc 7. Aitang Zhang, Aihua Li, Wei Zhao, Guowen Yan, Bingping Liu, Mengli Liu, Meixiu Li, Bingbing Huo Jingquan Liu,An efficient and self-guided chemo-photothermal drug loading system based on copolymer and transferrin decorated MoS2 nanodots for dually control 8. Aitang Zhang, Aihua Li, Wei Zhao, Guowen Yan, Bingping Liu, Mengli Liu, Meixiu Li, Bingbing Huo Jingquan Liu,An efficient and self-guided chemo-photothermal drug loading system based on copolymer and transferrin decorated MoS2 nanodots for dually control 9. Zhang, Aitang, et al. "A Target‐Directed Chemo‐Photothermal System Based on Transferrin and Copolymer‐Modified MoS2 Nanoplates with pH‐Activated Drug Release." Chemistry-A European Journal 23.47 (2017): 11346-11356.https://doi.org/10.1002/chem.201701916 10. Yang, Hui, et al." Intestinal absorption mechanisms of araloside A in situ single-pass intestinal perfusion and in vitro Caco-2 cell model." Biomedicine & Pharmacotherapy 106 (2018): 1563-1569.https://doi.org/10.1016/j.biopha.2018.07.117 11. Li, Guozhuan, et al. "Comparison of the chromatographic fingerprint, multicomponent quantitation and antioxidant activity of Salvia miltiorrhiza Bge. between sweating and nonsweating." Biomedical Chromatography 32.6 (2018): e4203.https://doi.org/10.1002/bm 12. Zhang, Li‐Ping, et al. "Effects of 1‐methylcyclopropene on the Metabolic Pathways of Aroma‐Related Compounds in N anguo Pear." Journal of Food Processing and Preservation 38.4 (2014): 1749-1758.https://doi.org/10.1111/jfpp.12138 13. [IF=13.273] Aitang Zhang et al."An efficient and self-guided chemo-photothermal drug loading system based on copolymer and transferrin decorated MoS2 nanodots for dually controlled drug release."Chem Eng J. 2018 Jun;342:120 14. [IF=4.952] Tahidul Islam et al."Phenolic profiles, antioxidant capacities and metal chelating ability of edible mushrooms commonly consumed in China."Lwt Food Sci Technol. 2016 Oct;72:423 15. [IF=4.759] Liai Lan et al."Fast and direct determination of catechol-3, 6-bis(methyleiminodiacetic acid) prototype in beagle dog plasma using liquid chromatography tandem mass spectrometry: A simplified and high throughput in-vivo method for the metal chelator."J Ch 16. [IF=4.545] Hui Yang et al."Intestinal absorption mechanisms of araloside A in situ single-pass intestinal perfusion and in vitro Caco-2 cell model."Biomed Pharmacother. 2018 Oct;106:1563 17. [IF=2.986] Song Xinfeng et al."In Vitro Safety Evaluation and In Vivo Imaging Studies of Superparamagnetic Iron Oxide Nanoparticles through Biomimetic Modification."J Nanomater. 2019;2019:9827625 18. [IF=2.19] Li-Ping Zhang et al."Effects of 1-methylcyclopropene on the Metabolic Pathways of Aroma-Related Compounds in Nanguo Pear."J Food Process Pres. 2014 Aug;38(4):1749-1758 19. [IF=1.902] Guozhuan Li et al."Comparison of the chromatographic fingerprint, multicomponent quantitation and antioxidant activity of Salvia miltiorrhiza Bge. between sweating and nonsweating."Biomed Chromatogr. 2018 Jun;32(6):e4203 20. [IF=12.479] Ziying Fei et al."Physiologically triggered injectable red blood cell-based gel for tumor photoablation and enhanced cancer immunotherapy."Biomaterials. 2021 Apr;271:120724 21. [IF=7.514] Baoshan He et al."Aptamer-based thin film gold electrode modified with gold nanoparticles and carboxylated multi-walled carbon nanotubes for detecting oxytetracycline in chicken samples."Food Chem. 2019 Dec;300:125179 22. [IF=7.514] Hongxia Tan et al.Zein structure and its hidden zearalenone: Effect of zein extraction methods.Food Chem. 2021 Nov;:131563 23. [IF=4.813] Zhao Puying et al."Characterization and heterologous expression of a novel Co2 -dependent leucyl aminopeptidase Amp0279 originating from Lysinibacillus sphaericus."Appl Microbiol Biot. 2022 Feb;106(3):1139-1149 |
Ethylenediaminetetraacetic acid - Nature
Open Data Verified Data
white crystalline powder. mp240 ~ 241 deg C (decomposition). Soluble in sodium hydroxide, sodium carbonate and ammonia, insoluble in general organic solvents. The solubility in water was 0.2g/10 og at 20 °c. When the temperature reached 150 °c, the carboxyl group was removed.
Last Update：2024-01-02 23:10:35
Ethylenediaminetetraacetic acid - Preparation Method
Open Data Verified Data
In ethylenediaminetetraacetic acid and water, with stirring, add 30% sodium hydroxide solution, heat to complete reaction, add hydrochloric acid to pH 4.5, concentrate, filter, cool crystallization, wash, ethylenediaminetetraacetic acid was obtained by drying.
Last Update：2022-01-01 09:25:19
Ethylenediaminetetraacetic acid - Introduction
Soluble in sodium hydroxide, sodium carbonate and ammonia solution, soluble in 161 boiling water, slightly soluble in cold water, insoluble in alcohol and general organic solvents.
Last Update：2022-10-16 17:26:53
Ethylenediaminetetraacetic acid - Use
Open Data Verified Data
complexing reagent. It is used as a masking agent for metal ion complexing agent and separation, detergent, blood anticoagulant and agricultural chemical spray.
Last Update：2022-01-01 09:25:19
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View History
Raw Materials for Ethylenediaminetetraacetic acid
Downstream Products for Ethylenediaminetetraacetic acid
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